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Cake day: June 16th, 2023

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  • Self Driving Cars - were getting used to the idea because of the half baked stuff that’s already here but it’s realistic this will make it mainstream in the coming years

    “Cure” for cancer - the rapid progress in immunotherapy drugs is making more and more cancers realistically treatable. Cancers.are still terrible conditions but it does feel realistic that we are moving towards a “cure”. After that it’ll be a focus on preventing and reducing the horrible side effects of treating cancers.

    Regrowing organs - this also seems increasingly realistic. We’re already routinely regrowing people’s immune systems for some conditions (autologus ransplants - where the donor is also the recipient). We’re also increasingly growing different types of tissues and organs in lab experoments. It’s looking plausible although hard to say when it’ll become mainstream.

    AI - I’m not convinced this one is on its way. What I mean is true General AI. What is labelled AI now is nowhere near General AI; it’s sophisticated and impressive but also limited and deeply flawed. We’re in an era of hype to drive up share prices but the actual technology is error strewn and is essentially a remix engine for human generated creativity. I’m not convinced true General AI is on its way because at the moment they don’t understand how the current AI systems work. It’s unlikely you can proceed from what we have to full general AI stumbling around in the dark or by shear luck. Not impossible, but unlikely. I think the current methods will more likely hit a brick wall in prpgress - they are useful tools but may be an illusion when it comes to full AI.




  • In fairness to Apple that is good design. Computers including phones should be intuitive and easy to use, but also accessible to more experienced users.

    The keeping up with Jones stuff with apple though is really bad. Like kids going off the university getting premium Mac books when they could save money and get a generic windows lap top. Or the seemingly ubiquitous purchase of earpods - an expensive way to purchase earphones when there are so many cheaper alternatives, not least the dirt cheap 3.5mm wired earphones that phone manufacturers are trying to obliterate.




  • Almost the whole of black Friday is a nonsense. The only things worth buying are things you would have bought anyway but know are on discount.

    Many items prices go up for a period before black Friday so they can then be discounted, and manufacturers even have cheaper versions of models of their products that they supply to discount chains and companies like Amazon for black Friday.

    The only things I’d buy on sale are items I’m watching via camelcamelcamel which have hit discount, or software on discount. There are a few specific items I need to buy that I might buy if they’re genuinely on discount but most of the stuff thrust in your face during the sales is cheap tat or lies.



  • True although I think most relationships are unstable and have drama particularly when young, which is why people can move through so many. Most people have multiple relationships in their lives until they find someone that works (or keep going). That’s seen as normal.

    I think there is a bias when people look at poly relationships as they seem novel and if they fail it’s easy to say it was because it was poly. But if a 2 partner relationship fails it’s “normal” and we accept all the reasons like “I didntnlove them anymore” or “we grew apart” etc.


  • It sounds like the person you were with would have been better off in an open relationship with someone.rather than labelling it as polyamory or want to pursue polyamory?

    I’ve not been in a ployamerous relationship myself but I’d imagine the hardest part is the time and effort needed to maintain your relationship with each partner?

    I could see 2 partners being doable but hard work, but once you go beyond that, then it must get very difficult? Especially if you don’t all live together as juggling full time work around making the time and space to maintain very close personal relationships must be very hard.

    And my mind boggles when you get to pplyamorpus “networks” where 2 partners may have relationships with other people rather than a shared 3rd partner. I think it would take a lot of honesty and maturity to make that work long term. I don’t think I’d be capable of that.


  • Polygamy does mean marriages but has been missed because people didn’t have better alternative words. “Menage a trois” is another term not needing marriage but has connotations to some of being mostly sexual and also only cover 3 people.

    Polyamory as a word wasn’t really widely used until the 90s and it’s only really become mainstream in the last maybe 10 years?

    Polyamory is much more precise and correct than polygamy.for describing relationships outside marriage. Polygamy is also a legal term very specifically related to marriage laws.


  • Yes - because the future of gaming is probably VR spaces so games on a 2D screen will become nostalgic to an extent.

    The nostalgia may be loading up a space with a virtual pc and playing an old game on a mouse and keyboard or controller.

    VR headsets aren’t yet there but but when they’re light weight and high definition enough, it may make more sense to play a game on a virtual screen which can be 40 inches or room scale, than your desktop. If I could see my hands and the mouse and keyboard I’d probably already be doing it. It already works with virtual desktop and controller based games.



  • So, alternative take. If you have a home PC would you be better upgrading it and getting a cheaper laptop for more basic use?

    Basically do you really need a mobile work horse? If you’re doing video work then you may be better with a graphics card or CPU upgrade £ for £. Do you really want to be editing videos on your sofa or in bed? It doesn’t seem like the easiest or most productive way to work in that particular use.

    You can also stream any game from your PC to a low power laptop (or other devices) using Steam or other streaming tech. The pc can be on but with the sound and screen off, while you’re elsewhere streaming a game.

    So maybe a PC upgrade and a shared basic laptop for video and internet would be enough? The only downside is if you genuinely think you would want to do full on video work on the go - out of the home or abroad for example. Then it makes more sense. But a powerful laptop around the house when you have a PC that does the same seems a bit pointless. It also means work drifts away into the rest of your home, whereas now when you’re not at your PC you’re not working.

    But if this is more talking yourself into buying an expensive toy, there may be better toys to be had for far less. Like a steam deck - under £400 for a decent machine, play games anywhere in the home (on the device or streaming to the device), get a dock and plug it in to your telly.

    Edit: other way to think of it: do you really need the laptop? What could you spend that money on instead? There is an opportunity cost if you spend that money or take on debt for something you don’t really need. You could save that £42 a month and treat yourself to something else in 6 months or a year.


  • So big mistake here: NAC is not harmless. It does have side effects and it also has toxicity at high doses.

    It has not been studied in long term use orally or IV, it’s main use bomg short term use for paracetamol overdose treatment. Inhalation is more studied but it is not absorbed into the body in the same way.

    We think it is safe but we haven’t actually done human trials to be sure. What we have found in mice is that high doses can cause lung and heart damage and also when it comes to alcohol it is protective if taken before alcohol consumption BUT it amplifies the toxicity to the liver if about 4 hours taken after alcohol. All of this is summarised on the Wikipedia page which looks to be good quality.

    Overall it may be a useful drug but don’t take it off label or self medicating. Medicine is littered with unexpected effects of drugs that only came out once it was too late. Thalidomide is a good example - a “wonder drug” for nausea used in pregnancy that was not tested and caused horrific birth defects which only became evident when it was too late.

    Your body is not a lab, be careful experimenting with supposedly “safe” drugs.


  • I think your second half is bang on the nail for the missing part of this story. It is not just to drive search directly, it is also to control the browser market long term.

    That’s what Microsoft did very successfully with Internet Explorer too. They have it away for free and bundled it with Windows, killing all competition and then used that to leverage MSN. They also didn’t follow standards and through market dominance shaped the internet.

    Google sort of follows standards but they have also forced through proprietary standards or have broken code which is why some websites don’t work well in Firefox or Safari even now.

    Chromium may be open source but it is a tool used by Google to control and dominate the internet.

    Apple is exactly the same with WebKit - they talk about privacy and security but the real motivation is surpressong alternate routes to the internet from their devices whic then keeps iron control over payment methods particularly in iOS. Yet people in the apple eco system buy into the narrative that the one piece of software you’re not allowed in iOS is a non apple web browser, as if that is an acceptable approach. It’s just another manifestation of anti competitive behaviour and the power and money you can get by “free” software.